Invention Grant
- Patent Title: ANF-RGC in-gene knock-out animal
- Patent Title (中): ANF-RGC基因敲除动物
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Application No.: US13476305Application Date: 2012-05-21
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Publication No.: US08835711B2Publication Date: 2014-09-16
- Inventor: Rameshwar K. Sharma , Teresa Duda
- Applicant: Rameshwar K. Sharma , Teresa Duda
- Applicant Address: US PA Elkins Park
- Assignee: Salus University
- Current Assignee: Salus University
- Current Assignee Address: US PA Elkins Park
- Agent J. Eric Sumner
- Main IPC: A01K67/027
- IPC: A01K67/027 ; C12N15/85
Abstract:
The present invention relates to transgenic animals comprising a mutation or deletion to the ANF-RGC protein, particularly to its ARM and/or its ATS-ST region. Such animals may be used to study the effects on pathways associated with ANF-RGC activation, including, but not limited to, hypertension. Such animals may also be used in drug screen assays, to establish toxicity profiles, or other similar methods discussed herein known in the art.
Public/Granted literature
- US20130291132A1 ANF-RGC IN-GENE KNOCK-OUT ANIMAL Public/Granted day:2013-10-31
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