Invention Grant
US08841089B2 Polynucleotides for enhancing expression of a polynucleotide of interest
有权
用于增强感兴趣的多核苷酸表达的多核苷酸
- Patent Title: Polynucleotides for enhancing expression of a polynucleotide of interest
- Patent Title (中): 用于增强感兴趣的多核苷酸表达的多核苷酸
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Application No.: US12593240Application Date: 2008-03-28
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Publication No.: US08841089B2Publication Date: 2014-09-23
- Inventor: Manfred Frey , Heiko Flammann , Mathias Hafner
- Applicant: Manfred Frey , Heiko Flammann , Mathias Hafner
- Applicant Address: DE Mannheim
- Assignee: Hochschule Mannheim
- Current Assignee: Hochschule Mannheim
- Current Assignee Address: DE Mannheim
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: EP07105109 20070328
- International Application: PCT/EP2008/053716 WO 20080328
- International Announcement: WO2008/116931 WO 20081002
- Main IPC: C12P21/00
- IPC: C12P21/00 ; C12N15/85 ; C12N9/12 ; C12P21/06 ; C12P21/04 ; C12N5/00 ; C12N5/02 ; C12N5/07 ; C12N5/10 ; C12N15/00 ; C07H21/00 ; C07H21/02 ; C07H21/04 ; A61K48/00
Abstract:
The present invention relates to polynucleotides comprising a first nucleic acid sequence for a chromatin element, which is capable of enhancing expression, and at least one second nucleic acid sequence comprising a curved origin motif. Furthermore, the invention relates to a host cell, a non-human transgenic organism, a vector and a kit comprising the aforementioned polynucleotide. Moreover, the invention relates to methods for expressing a polynucleotide of interest.
Public/Granted literature
- US20100113574A1 POLYNUCLEOTIDES FOR ENHANCING EXPRESSION OF A POLYNUCLEOTIDE OF INTEREST Public/Granted day:2010-05-06
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