Invention Grant
- Patent Title: Cell-based production of nonulosonates
- Patent Title (中): 基于细胞的非类胡萝卜素生产
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Application No.: US13642308Application Date: 2011-04-20
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Publication No.: US08841099B2Publication Date: 2014-09-23
- Inventor: Christopher N. Boddy , Susan M. Logan , Benjamin R. Lundgren , Ian C. Schoenhofen , Dennis M. Whitfield
- Applicant: Christopher N. Boddy , Susan M. Logan , Benjamin R. Lundgren , Ian C. Schoenhofen , Dennis M. Whitfield
- Applicant Address: CA Ottawa, ON CA Ottawa, ON
- Assignee: National Research Council of Canada,University of Ottawa
- Current Assignee: National Research Council of Canada,University of Ottawa
- Current Assignee Address: CA Ottawa, ON CA Ottawa, ON
- Agency: Pasternak Patent Law
- Agent Dahna S. Pasternak
- International Application: PCT/CA2011/000449 WO 20110420
- International Announcement: WO2011/130836 WO 20111027
- Main IPC: C12P7/40
- IPC: C12P7/40 ; C12P7/42 ; C12P1/02 ; C12N1/14 ; A61K38/00 ; C12N15/52 ; C12N15/70 ; C12P19/30 ; C12P19/26

Abstract:
The present invention relates to the cell-based production of bacterial nonulosonates and their biosynthetic precursors. Specifically, the present invention provides recombinant cells for the production of pseudaminic acid, legionaminic acid, UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose, and UDP-2,4-diacetamido-2,4,6-trideoxy-α-D-glucopyranose. Methods for producing the sugars are also provided.
Public/Granted literature
- US20130196381A1 CELL-BASED PRODUCTION OF NANULOSONATES Public/Granted day:2013-08-01
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