Invention Grant
- Patent Title: Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications
- Patent Title (中): 荧光共振能量转移检测纳米颗粒用于体外和体内应用
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Application No.: US12201190Application Date: 2008-08-29
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Publication No.: US08841134B2Publication Date: 2014-09-23
- Inventor: Rao Papineni , John William Harder , William E. McLaughlin , Douglas Lincoln Vizard , Tao Ji
- Applicant: Rao Papineni , John William Harder , William E. McLaughlin , Douglas Lincoln Vizard , Tao Ji
- Applicant Address: US MA Billerica
- Assignee: Bruker Biospin Corporation
- Current Assignee: Bruker Biospin Corporation
- Current Assignee Address: US MA Billerica
- Agency: O'Shea Getz P.C.
- Main IPC: G01N21/76
- IPC: G01N21/76 ; G01N33/533 ; G01N33/542 ; G01N33/543 ; C08G65/332 ; C08G65/334 ; C08G65/333
Abstract:
A combination of nanoparticles is disclosed comprised of amine functionalized polyethylene glycol in which one particle with a fluorescent donor dye having one wavelength excitation maximum and at least one additional particle with a second fluorescent dye having a second, higher wavelength excitation maximum, the particles having the same or different biomolecule targeting moieties bound to their external surfaces.
Public/Granted literature
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