Invention Grant
- Patent Title: Heterocyclic derivatives
- Patent Title (中): 杂环衍生物
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Application No.: US13501587Application Date: 2010-10-11
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Publication No.: US08841289B2Publication Date: 2014-09-23
- Inventor: Paul David Ratcliffe , Thomas Russell Clarkson , Fiona Jeremiah , John Kinnard Ferguson MacLean
- Applicant: Paul David Ratcliffe , Thomas Russell Clarkson , Fiona Jeremiah , John Kinnard Ferguson MacLean
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme B.V.
- Current Assignee: Merck Sharp & Dohme B.V.
- Current Assignee Address: US NJ Rahway
- Agent Keith D. MacMillan; John C. Todaro
- Priority: EP09172872 20091013
- International Application: PCT/EP2010/065160 WO 20101011
- International Announcement: WO2011/045258 WO 20110421
- Main IPC: C07D487/08
- IPC: C07D487/08 ; C07D519/00 ; C07D471/08 ; A61K31/551 ; A61K31/517 ; A61K31/55
Abstract:
The present invention relates to a heterocyclic derivative of formula (I) wherein the variables are as defined in the specification or to a pharmaceutically acceptable salt or solvate thereof. The present invention further relates to pharmaceutical compositions comprising said heterocyclic derivatives and to their use in therapy, for instance in the treatment or prevention of disorders mediated by nicotinic acetylcholine receptors, such as schizophrenia and Alzheimer's disease.
Public/Granted literature
- US20120208796A1 HETEROCYCLIC DERIVATIVES Public/Granted day:2012-08-16
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