Invention Grant
- Patent Title: Melt-processed imatinib dosage form
- Patent Title (中): 熔融加工的伊马替尼剂型
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Application No.: US12447508Application Date: 2007-11-08
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Publication No.: US08841303B2Publication Date: 2014-09-23
- Inventor: Jörg Breitenbach , Norbert Steiger , Harald Hach , Ulrich Westedt , Martin Knobloch , Ralf Altenburger , Nicoletta Loggia , Jörg Ogorka
- Applicant: Jörg Breitenbach , Norbert Steiger , Harald Hach , Ulrich Westedt , Martin Knobloch , Ralf Altenburger , Nicoletta Loggia , Jörg Ogorka
- Applicant Address: DE Wiesbaden CH Basel
- Assignee: Abbvie Deutschland GmbH & Co. KG,Novartis AG
- Current Assignee: Abbvie Deutschland GmbH & Co. KG,Novartis AG
- Current Assignee Address: DE Wiesbaden CH Basel
- Agency: Saul Ewing, LLP
- Agent Peter C. Lauro, Esq.
- Priority: EP06023367 20061109
- International Application: PCT/EP2007/062100 WO 20071108
- International Announcement: WO2008/055965 WO 20080515
- Main IPC: A61K31/497
- IPC: A61K31/497 ; A61K9/20

Abstract:
The invention provides a dosage form, comprising a melt-processed mixture of (a) a pharmaceutically effective amount of imatinib or a salt thereof, (b) at least one polymeric binder, and (c) at least one pharmaceutically acceptable non-ionic surfactant. The invention provides imatinib dosage forms with high drug loading which can be prepared in a simple and efficient manner, imatinib dosage forms from which the active principle is released in an essentially pH-independent fashion, and extended release imatinib dosage forms.
Public/Granted literature
- US20100240672A1 MELT-PROCESSED IMATINIB DOSAGE FORM Public/Granted day:2010-09-23
Information query
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