Invention Grant
- Patent Title: Substituted pyrazines and their use in the treatment of disease
- Patent Title (中): 取代的吡嗪及其在治疗疾病中的应用
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Application No.: US14033552Application Date: 2013-09-23
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Publication No.: US08841309B2Publication Date: 2014-09-23
- Inventor: Dieter Hamprecht , Armin Heckel , Joerg Kley
- Applicant: Dieter Hamprecht , Armin Heckel , Joerg Kley
- Applicant Address: DE Ingelheim am Rheim
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rheim
- Agent Michael P. Morris; Edward S. Lazer
- Priority: EP12185631 20120924
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D241/16 ; C07D401/12 ; A61K31/498 ; C07D241/32 ; C07D453/02 ; A61K31/5377 ; A61K45/06 ; A61K31/497 ; C07D471/08 ; C07D403/12
Abstract:
The present invention relates to compounds of general formula (I) and the tautomers and the salts thereof, particularly the pharmaceutically acceptable salts thereof, which have valuable pharmacological properties, particularly an inhibitory effect on epithelial sodium channels, the use thereof for the treatment of diseases, particularly diseases of the lungs and airways.
Public/Granted literature
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