Invention Grant
- Patent Title: 1,5-naphthyridine derivative or salt thereof
- Patent Title (中): 1,5-萘啶衍生物或其盐
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Application No.: US14166105Application Date: 2014-01-28
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Publication No.: US08841456B2Publication Date: 2014-09-23
- Inventor: Hidetomo Furuyama , Hideki Kurihara , Kentarou Furuya , Takahiro Terao , Shinichirou Sekine , Daisuke Nakagawa
- Applicant: FUJIFILM Corporation
- Applicant Address: JP Tokyo
- Assignee: FUJIFILM Corporation
- Current Assignee: FUJIFILM Corporation
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2011-167489 20110729
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07F7/10 ; C07D519/00

Abstract:
A 1,5-naphthyridine derivative represented by Formula [1] (in which R1, R2, R3, R4 and R5 represent a hydrogen atom, -L-Z (in which Z represents a non-aromatic heterocyclic group or the like; and L represents a single bond or the like), or the like, R6 represents -L-Z or the like, R7 and R8 represent a hydrogen atom or the like, and Q represents an oxygen atom or the like), or a salt thereof has an excellent inhibitory activity with respect to the PI3K-AKT pathway and the Ras-Raf-MEK-ERK pathway, and is useful for treatments such as prophylactic treatments and therapeutic treatments of diseases in which the PI3K-AKT pathway and the Ras-Raf-MEK-ERK pathway are involved.
Public/Granted literature
- US20140142302A1 1,5-NAPHTHYRIDINE DERIVATIVE OR SALT THEREOF Public/Granted day:2014-05-22
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