Methods and systems for positioning detectors for Nuclear Medicine (NM) imaging are provided. One system includes a gantry supporting one or more imaging detectors, wherein the gantry has a portion configured for movable operation. The system also includes a table on one side of the gantry configured to support a patient thereon, wherein the table is further configured to move within an opening of the gantry. The system further includes a patient support device movably positioned on an opposite side of the gantry from the table, wherein the patient support device is configured for movable operation.