An over-current protection device includes a resistive device, an insulation layer, an electrode layer and at least one electrically conductive connecting member. The resistive device includes a first electrode foil, a second electrode foil and a positive temperature coefficient (PTC) material layer laminated between the electrode foils. The insulation layer is formed on the surface of the first electrode foil, and the electrode layer is formed on the surface of the insulation layer. The conductive connecting member penetrates the electrode layer, the insulation layer and the first electrode foil for electrically connecting the electrode layer and the first electrode foil. The conductive connecting member is insulated from the second electrode foil. One of the first and second electrode foils is configured to electrically connect to a protective circuit module (PCM), and the other one is configured to electrically connect to an electrode terminal of a battery to be protected.