Invention Grant
US08845880B2 Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
有权
基于纳米孔的单DNA分子表征，使用速度凸块的鉴定和分离
- Patent Title: Nanopore-based single DNA molecule characterization, identification and isolation using speed bumps
- Patent Title (中): 基于纳米孔的单DNA分子表征，使用速度凸块的鉴定和分离
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Application No.: US13333932Application Date: 2011-12-21
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Publication No.: US08845880B2Publication Date: 2014-09-30
- Inventor: Randall W. Davis , Roger J. A. Chen
- Applicant: Randall W. Davis , Roger J. A. Chen
- Applicant Address: US CA Mountain View
- Assignee: Genia Technologies, Inc.
- Current Assignee: Genia Technologies, Inc.
- Current Assignee Address: US CA Mountain View
- Agent Victoria L. Boyd
- Main IPC: G01N33/50
- IPC: G01N33/50 ; B82Y15/00 ; C12Q1/68 ; G01N33/487 ; B82Y10/00
Abstract:
The present invention relates to a method of using nanopores to obtain sequence information of sample DNAs in ss test DNAs. The method comprises using speed bumps to stall the ss test DNAs in the nanopores at random positions of the ss test DNAs to obtain sequence information of each and every nucleotides of the sample DNAs, and to construct the whole sequences of the sample DNAs. The present invention also relates to identification and/or isolation of test DNAs having desired sequence(s) using nanopore detectors facilitated by speed bump.
Public/Granted literature
- US20120160681A1 NANOPORE-BASED SINGLE DNA MOLECULE CHARACTERIZATION, IDENTIFICATION AND ISOLATION USING SPEED BUMPS Public/Granted day:2012-06-28
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