Invention Grant
US08846102B2 Non-viral compositions and methods for transfecting gut cells in vivo
有权
用于体内转染肠细胞的非病毒组合物和方法
- Patent Title: Non-viral compositions and methods for transfecting gut cells in vivo
- Patent Title (中): 用于体内转染肠细胞的非病毒组合物和方法
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Application No.: US11694852Application Date: 2007-03-30
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Publication No.: US08846102B2Publication Date: 2014-09-30
- Inventor: Anthony T. Cheung , Eric C. Hsu
- Applicant: Anthony T. Cheung , Eric C. Hsu
- Applicant Address: unknown Vancouver, BC
- Assignee: enGene, Inc.
- Current Assignee: enGene, Inc.
- Current Assignee Address: unknown Vancouver, BC
- Agency: Arnold & Porter
- Agent Todd Lorenz
- Main IPC: A61K9/50
- IPC: A61K9/50 ; C12N5/071 ; A61K48/00 ; A61K47/36 ; A61K9/51
Abstract:
The present invention provides chitosan-based nanoparticles that can protect nucleic acids and deliver the same into gut mucosal cells. Compositions and methods for the expression of therapeutic nucleic acids in cells of the gut mucosa are provided. Compositions and methods for delivering therapeutic proteins systemically from cells of the gut mucosa are also provided.
Public/Granted literature
- US20110171314A1 NON-VIRAL COMPOSITIONS AND METHODS FOR TRANSFECTING GUT CELLS IN VIVO Public/Granted day:2011-07-14
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