Invention Grant
- Patent Title: Anti-inflammatory cyclooxygenase inhibitors
- Patent Title (中): 抗炎环氧合酶抑制剂
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Application No.: US14072748Application Date: 2013-11-05
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Publication No.: US08846115B2Publication Date: 2014-09-30
- Inventor: Eric Hauser Kuhrts
- Applicant: Metaproteomics, LLC
- Applicant Address: US CA San Clemente
- Assignee: Metaproteomics, Inc.
- Current Assignee: Metaproteomics, Inc.
- Current Assignee Address: US CA San Clemente
- Agency: McDermott Will & Emery LLP
- Main IPC: A01N65/00
- IPC: A01N65/00 ; A61K31/201 ; A61K31/122
Abstract:
Disclosed is a pharmaceutical composition including a therapeutic quantity of a COX-2 inhibitor having an IC50-WHMA COX-2/COX-1 ratio ranging from about 0.23 to about 3.33 with reduced gastrointestinal and cardiovascular toxicity. Also disclosed are methods for treating osteoarthritis, rheumatoid arthritis or acute pain with less side-effects and faster onset of action utilizing the disclosed pharmaceutical composition.
Public/Granted literature
- US20140066520A1 NOVEL ANTI-INFLAMMATORY CYCLOOXYGENASE INHIBITORS Public/Granted day:2014-03-06
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