Invention Grant
US08846311B2 Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease
有权
映射激酶激酶激酶3(MAP4K3)作为自身免疫疾病,癌症,炎症和IL-17相关疾病的生物标志物和治疗靶标
- Patent Title: Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease
- Patent Title (中): 映射激酶激酶激酶3(MAP4K3)作为自身免疫疾病,癌症,炎症和IL-17相关疾病的生物标志物和治疗靶标
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Application No.: US13548212Application Date: 2012-07-13
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Publication No.: US08846311B2Publication Date: 2014-09-30
- Inventor: Tse-Hua Tan , Huai-Chia Chuang
- Applicant: Tse-Hua Tan , Huai-Chia Chuang
- Applicant Address: TW Miaoli County
- Assignee: National Health Research Institutes
- Current Assignee: National Health Research Institutes
- Current Assignee Address: TW Miaoli County
- Agency: Intellectual Property Connections, Inc.
- Agent Hsiu-Ming Saunders
- Main IPC: C12Q1/00
- IPC: C12Q1/00 ; C12Q1/68 ; G01N33/567 ; G01N33/574 ; G01N33/50

Abstract:
Methods for identifying a therapeutic agent for treating a Germinal Center Kinase (GCK)-Like Kinase (GLK)-mediated disease are disclosed. Methods for detecting a modulation of GLK signaling by a test compound are disclosed. Also disclosed are methods for detecting the presence and/or severity of an autoimmune disease and/or cancer.
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