Invention Grant
US08846364B2 Method to improve the stability and broaden the pH range of family G/11 xylanases
有权
提高G / 11木聚糖酶稳定性和扩大pH范围的方法
- Patent Title: Method to improve the stability and broaden the pH range of family G/11 xylanases
- Patent Title (中): 提高G / 11木聚糖酶稳定性和扩大pH范围的方法
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Application No.: US13849465Application Date: 2013-03-22
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Publication No.: US08846364B2Publication Date: 2014-09-30
- Inventor: Fred Fenel , Ossi Turunen , Matti Leisola
- Applicant: Danisco US Inc.
- Applicant Address: US CA Palo Alto
- Assignee: Danisco US Inc.
- Current Assignee: Danisco US Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Danisco US Inc.
- Priority: FI19992186 19991012; FI20001580 20000703
- Main IPC: C12N9/24
- IPC: C12N9/24 ; C12N9/42 ; C07H21/04 ; D06M16/00 ; A23K1/00 ; A23K3/00
Abstract:
The present invention relates to protein engineering, and concerns especially family G/11 xylanases, and genes encoding said enzymes. In specific, the invention concerns Trichoderma reesei XYNII gene, which codes for endo-1,4-β-xylanase (EC 3.2.1.8). The invention describes how site-directed mutagenesis can be used to improve the properties of an enzyme to match the industrial conditions where it is used. Protein engineering can be used to improve thermoactivity and thermostability of xylanases, as well as to broaden their pH range.
Public/Granted literature
- US20130288335A1 METHOD TO IMPROVE THE STABILITY AND BROADEN THE PH RANGE OF FAMILY G/11 XYLANASES Public/Granted day:2013-10-31
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