Invention Grant
- Patent Title: Targeted gene modification by parvoviral vectors
- Patent Title (中): 通过细小病毒载体靶向基因修饰
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Application No.: US13114117Application Date: 2011-05-24
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Publication No.: US08846387B2Publication Date: 2014-09-30
- Inventor: David W. Russell , Roli K. Hirata
- Applicant: David W. Russell , Roli K. Hirata
- Applicant Address: US WA Seattle
- Assignee: The University of Washington
- Current Assignee: The University of Washington
- Current Assignee Address: US WA Seattle
- Agency: Nixon Peabody LLP
- Agent Mark J. FitzGerald
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N15/63 ; C12N15/87 ; A01N63/00 ; C12N15/86 ; A01K67/00
Abstract:
This invention provides methods for obtaining targeted gene modification in vertebrate cells using parvoviral vectors, including adeno-associated virus (AAV). The parvoviral vectors used in the methods of the invention are capable of targeting a specific genetic modification to a preselected target locus in a cellular genome by homologous pairing.
Public/Granted literature
- US20120070890A1 TARGETED GENE MODIFICATION BY PARVOVIRAL VECTORS Public/Granted day:2012-03-22
Information query
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