Invention Grant
- Patent Title: Thiopyrimidine-based compounds and uses thereof
- Patent Title (中): 硫基嘧啶类化合物及其用途
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Application No.: US12524849Application Date: 2008-01-31
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Publication No.: US08846704B2Publication Date: 2014-09-30
- Inventor: David Gerard Bourke , Xianyong Bu , Christopher John Burns , Anthony Nicholas Cuzzupe , John Thomas Feutrill , Tracy Leah Nero , Beata Maria Blannin , Jun Zeng , Shaun Patrick Gaynor
- Applicant: David Gerard Bourke , Xianyong Bu , Christopher John Burns , Anthony Nicholas Cuzzupe , John Thomas Feutrill , Tracy Leah Nero , Beata Maria Blannin , Jun Zeng , Shaun Patrick Gaynor
- Applicant Address: US CA Foster City
- Assignee: YM Biosciences Austraila Pty Ltd
- Current Assignee: YM Biosciences Austraila Pty Ltd
- Current Assignee Address: US CA Foster City
- International Application: PCT/AU2008/000103 WO 20080131
- International Announcement: WO2008/092199 WO 20080807
- Main IPC: A01N43/54
- IPC: A01N43/54 ; A61K31/505 ; C07D239/02
Abstract:
The present invention relates to thiopyrimidine-based compounds that are inhibitors of protein kinases including JAK kinases. In particular, the compounds are selective for JAK1, JAK2 or JAK3 kinases and combinations thereof such as JAK1 and JAK2. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases and vascular diseases.
Public/Granted literature
- US20100239631A1 THIOPYRIMIDINE-BASED COMPOUNDS AND USES THEREOF Public/Granted day:2010-09-23
Information query
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