Invention Grant
US08846724B2 Compositions for treating obesity and insulin resistance disorders
有权
用于治疗肥胖症和胰岛素抵抗障碍的组合物
- Patent Title: Compositions for treating obesity and insulin resistance disorders
- Patent Title (中): 用于治疗肥胖症和胰岛素抵抗障碍的组合物
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Application No.: US13192011Application Date: 2011-07-27
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Publication No.: US08846724B2Publication Date: 2014-09-30
- Inventor: David A. Sinclair , Maria Alexander-Bridges
- Applicant: David A. Sinclair , Maria Alexander-Bridges
- Applicant Address: US MA Cambridge US MA Boston
- Assignee: President and Fellows of Harvard College,The General Hospital Corporation
- Current Assignee: President and Fellows of Harvard College,The General Hospital Corporation
- Current Assignee Address: US MA Cambridge US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/35 ; A61K31/155 ; A61K31/12 ; A61K31/05 ; A61K31/7048 ; A61K31/353 ; A61K31/00
Abstract:
Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.
Public/Granted literature
- US20120029065A1 COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS Public/Granted day:2012-02-02
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