Invention Grant
- Patent Title: Mono quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors
- Patent Title (中): 单季铵盐和调节神经元烟碱乙酰胆碱受体的方法
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Application No.: US12304955Application Date: 2007-06-15
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Publication No.: US08846937B2Publication Date: 2014-09-30
- Inventor: Peter Crooks , Linda P. Dwoskin , Guangrong Zheng , Sangeetha Sumithran , Zhenfa Zheng
- Applicant: Peter Crooks , Linda P. Dwoskin , Guangrong Zheng , Sangeetha Sumithran , Zhenfa Zheng
- Applicant Address: US KY Lexington
- Assignee: University of Kentucky Research Foundation
- Current Assignee: University of Kentucky Research Foundation
- Current Assignee Address: US KY Lexington
- Agency: Crowell & Moring LLP
- International Application: PCT/US2007/014192 WO 20070615
- International Announcement: WO2007/149392 WO 20071227
- Main IPC: A61K31/435
- IPC: A61K31/435 ; C07D213/18 ; C07D213/30 ; C07D217/10 ; C07D213/20 ; C07D215/10 ; C07C17/16 ; C07D401/06
Abstract:
Provided are monoquaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.
Public/Granted literature
- US20100113511A1 Mono Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors Public/Granted day:2010-05-06
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