A home base station (HBS) (104, 801) performs radio channel measurements to detect one or more user equipments (UEs) (107) not served by the HBS which may be in a potentially interfering environment caused at least in part by the HBS. A database (812) of historical channel data (channel fingerprinting) of the HBS coverage area is used to predict the channel conditions and expected interference signal power seen by the detected UE(s). Based on a combination of the radio measurements (813) and historical channel data, the HBS can accurately and adaptively reduce its transmit power to a level that reduces or eliminates interference with the detected UE(s), while also not significantly degrading communication quality between other UEs served by the HBS.