Invention Grant
US08865644B2 Rapamycin formulation using recombinant high-density lipoprotein including apolipoprotein A-I and a mutant thereof
有权
雷帕霉素制剂使用重组高密度脂蛋白，包括载脂蛋白A-1及其突变体
- Patent Title: Rapamycin formulation using recombinant high-density lipoprotein including apolipoprotein A-I and a mutant thereof
- Patent Title (中): 雷帕霉素制剂使用重组高密度脂蛋白，包括载脂蛋白A-1及其突变体
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Application No.: US13881857Application Date: 2011-10-25
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Publication No.: US08865644B2Publication Date: 2014-10-21
- Inventor: Kyung-Hyun Cho
- Applicant: Kyung-Hyun Cho
- Applicant Address: KR Gyeongsan-si, Gyeongsandbuk-do
- Assignee: Industry-Academic Cooperation Foundation, Yeungnam University
- Current Assignee: Industry-Academic Cooperation Foundation, Yeungnam University
- Current Assignee Address: KR Gyeongsan-si, Gyeongsandbuk-do
- Agency: Sherr & Jiang PLLC
- Priority: KR10-2010-0104942 20101026
- International Application: PCT/KR2011/007966 WO 20111025
- International Announcement: WO2012/057492 WO 20120503
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K31/439 ; A61K9/127 ; C07K14/775 ; A61K31/436
Abstract:
Provided is a rapamycin formulation using a recombinant high-density lipoprotein including apolipoprotein mutant, the rapamycin formulation in which solubility of rapamycin and medical use, such as aging suppression and arteriosclerosis suppression, are improved by using recombinant high-density lipoprotein including apolipoprotein A-I and its mutant V156K.
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