Invention Grant
- Patent Title: Aminoglycosides: synthesis and use as antifungals
- Patent Title (中): 氨基糖苷类：合成和用作抗真菌剂
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Application No.: US13316720Application Date: 2011-12-12
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Publication No.: US08865665B2Publication Date: 2014-10-21
- Inventor: Cheng-Wei T. Chang , Jon Takemoto
- Applicant: Cheng-Wei T. Chang , Jon Takemoto
- Applicant Address: US UT Logan
- Assignee: Utah State University
- Current Assignee: Utah State University
- Current Assignee Address: US UT Logan
- Main IPC: C07H15/234
- IPC: C07H15/234 ; A61K31/7036 ; A01N43/16 ; C07H13/06 ; C07H5/06 ; C07H15/22 ; C07H11/00
Abstract:
The present invention relates to novel aminoglycoside analogs having certain substituents at the 6 position of ring III which exhibit improved antifungal activity but possess minimal antibacterial properties. The compounds of the present invention are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
Public/Granted literature
- US20120316125A1 AMINOGLYCOSIDES: SYNTHESIS AND USE AS ANTIFUNGALS Public/Granted day:2012-12-13
Information query
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