Invention Grant
US08865671B2 RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
有权
RNAi介导的脾脏酪氨酸激酶相关炎症状态的抑制
- Patent Title: RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
- Patent Title (中): RNAi介导的脾脏酪氨酸激酶相关炎症状态的抑制
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Application No.: US13172964Application Date: 2011-06-30
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Publication No.: US08865671B2Publication Date: 2014-10-21
- Inventor: John M. Yanni , Jon E. Chatterton , Daniel A. Gamache , Steven T. Miller
- Applicant: John M. Yanni , Jon E. Chatterton , Daniel A. Gamache , Steven T. Miller
- Applicant Address: US TX Fort Worth
- Assignee: Alcon Research, Ltd.
- Current Assignee: Alcon Research, Ltd.
- Current Assignee Address: US TX Fort Worth
- Main IPC: C12N15/113
- IPC: C12N15/113 ; C07H21/02
Abstract:
RNA interference is provided for inhibition of spleen tyrosine kinase (Syk) mRNA expression, in particular, for treating patients having a Syk-related inflammatory condition or at risk of developing a Syk-related inflammatory condition such as allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma, allergy, or mast-cell disease.
Public/Granted literature
- US20110288157A1 RNAi-Mediated Inhibition of Spleen Tyrosine Kinase-Related Inflammatory Conditions Public/Granted day:2011-11-24
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