Invention Grant
- Patent Title: Monitoring and modulating HGF/HGFR activity
- Patent Title (中): 监测和调节HGF / HGFR活性
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Application No.: US13606490Application Date: 2012-09-07
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Publication No.: US08865673B2Publication Date: 2014-10-21
- Inventor: Michael Detmar , Kentaro Kajiya
- Applicant: Michael Detmar , Kentaro Kajiya
- Applicant Address: US MA Boston
- Assignee: The General Hospital Corporation
- Current Assignee: The General Hospital Corporation
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07K14/475 ; G01N33/50 ; A61K38/18
Abstract:
Provided are methods and compositions for the modulation of hepatocyte growth factor activity to regulate lymphatic vessel development and function. Methods and composition for the monitoring and treatment of skin disorders, lymphedema, and metastatic cancers are disclosed. Also described are methods of identifying inhibitors of hepatocyte growth factor dependent lymphangiogenesis.
Public/Granted literature
- US20130064833A1 Monitoring and Modulating HGF/HGFR Activity Public/Granted day:2013-03-14
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