Invention Grant
US08865686B2 Tetracycline compounds as tyrosyl-DNA phosphodiesterase I inhibitors
有权
四环素类化合物作为酪氨酰-DNA磷酸二酯酶I抑制剂
- Patent Title: Tetracycline compounds as tyrosyl-DNA phosphodiesterase I inhibitors
- Patent Title (中): 四环素类化合物作为酪氨酰-DNA磷酸二酯酶I抑制剂
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Application No.: US12241011Application Date: 2008-09-29
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Publication No.: US08865686B2Publication Date: 2014-10-21
- Inventor: Yves Pommier , Laurent Thibaut , Christophe Marchand
- Applicant: Yves Pommier , Laurent Thibaut , Christophe Marchand
- Applicant Address: US DC Washington
- Assignee: The United States of America, as Represented by the Secretary, Dept. of Health and Human Services
- Current Assignee: The United States of America, as Represented by the Secretary, Dept. of Health and Human Services
- Current Assignee Address: US DC Washington
- Agency: Cantor Colburn LLP
- Main IPC: A61K31/65
- IPC: A61K31/65 ; A61P35/00 ; C07D499/21 ; C07C237/26 ; C07D295/13
Abstract:
The instant invention is directed towards tetracycline compositions, and methods of inhibiting Tdp1 activity, and methods of treating Tdp1-associated disorders.
Public/Granted literature
- US20090176747A1 TETRACYCLINE COMPOUNDS AND METHODS OF TREATMENT Public/Granted day:2009-07-09
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