Invention Grant
- Patent Title: Phenylimidazole derivatives as PDE10A enzyme inhibitors
- Patent Title (中): 苯基咪唑衍生物作为PDE10A酶抑制剂
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Application No.: US13365504Application Date: 2012-02-03
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Publication No.: US08865711B2Publication Date: 2014-10-21
- Inventor: Andreas Ritzén , Jan Kehler , Morten Langgård , Jacob Nielsen , John Paul Kilburn , Mohamed M. Farah
- Applicant: Andreas Ritzén , Jan Kehler , Morten Langgård , Jacob Nielsen , John Paul Kilburn , Mohamed M. Farah
- Applicant Address: DK Valby
- Assignee: H. Lundbeck A/S
- Current Assignee: H. Lundbeck A/S
- Current Assignee Address: DK Valby
- Agent Mary Catherine Di Nunzio
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D471/04 ; C07D403/12
Abstract:
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
Public/Granted literature
- US20120135987A1 NOVEL PHENYLIMIDAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS Public/Granted day:2012-05-31
Information query
