A high-power pulse light generator includes: a master oscillator generating oscillated pulse light in synchronization with a master clock signal; an optical amplifier amplifying the oscillated pulse light output from the master oscillator and outputting high-power pulsed light; a driving unit driving a pumping semiconductor laser in synchronization with the master clock signal; and a control unit controlling the driving unit so that the driving current to be supplied to the pumping semiconductor laser becomes lower than or equal to a set value at which the pumping semiconductor laser is not in a laser oscillation state when returning light from an irradiated body with the high-power pulsed light reaches the pumping semiconductor laser connected to the optical amplifier, the control unit determining a timing of the control in accordance with an optical path length between the irradiated body and the pumping semiconductor laser.