A distributed storage system has multiple instances. There is a plurality of local instances, and at least some of the local instances are at physically distinct geographic locations. Each local instance is configured to store data for a non-empty set of blobs in a plurality of data stores having a plurality of distinct data store types. In addition, each local instance stores metadata for the respective set of blobs in a metadata store distinct from the data stores. There is also a plurality of global instances. Each global instance is configured to store data for zero or more blobs in zero or more data stores and store metadata for all blobs stored at any local or global instance. The system selects one global instance to run a replication module that replicates blobs between instances according to blob policies.