Methods and apparatus for predicting an underflow condition associated with a floating-point multiply-add operation are disclosed. An example apparatus obtains a first operand value and a second operand value. The example apparatus then determines if the second operand value subtracted from the first operand value is greater than a minimum value and determines if the first operand value is greater than a sum value associated with a minimum operand value. The example apparatus then asserts an output signal indicative of an absence of an underflow condition associated with a floating-point value based on conditions associated with determining whether the second operand value subtracted from the first operand value is greater than the minimum value and determining if the first operand value is greater than the sum value.