The present invention relates to artwork preservation, and more particularly to an artwork preservation system that utilizes vacuum and is particularly suited to framed artwork. The artwork preservation system includes: a pair of corrugated planar members constructed and arranged to overlap a front side and back side of an artwork; at least one securing element, such as hook and loop fastener, for mating the first and second corrugated boards when the artwork is placed there between; a layer of air cushioning; and a sealable bag. The system may further include a vacuum pump for removing air from the sealable bag.