A mobile building transportation device can comprise a frame, a front axle, and a rear axle. The frame can support a mobile building for transport on a public highway and can include left and right longitudinal support members and front and rear transverse support members that bear at least a portion of the weight of the mobile building. The front and rear axles can each be coupled to the frame by suspension components. The front and rear transverse support members can be configured to support the mobile building above the front and/or rear axles to facilitate minimizing a vertical distance between the mobile building and the front and/or rear axles. This can minimize a height of a center of gravity of the mobile building and facilitate unobstructed movement of the front and rear axles through a range of motion of the front and/or rear suspension components. At least one of the longitudinal and transverse support members can be constructed, at least in part, of tubing.