An apparatus and method for use in the biopharmaceutical and chemical industries to facilitate the temporary attachment of standard laboratory glassware to vibratory mixers and other types of aggressive shaking equipment. The container holder couples the entire flask or container to the mixing equipment in a secure fashion. The technology may be used with conventional glass flasks, or with plastic flasks that can be configured for either single-use or multiple-use. The invention allows for single handed, low force insertion of the flaskware as well as the incorporation of sensors into the container holder.