Invention Grant
- Patent Title: Bone repair putty
- Patent Title (中): 骨修复腻子
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Application No.: US12910195Application Date: 2010-10-22
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Publication No.: US08876532B2Publication Date: 2014-11-04
- Inventor: Brent L. Atkinson , Tracey S. Hanks
- Applicant: Brent L. Atkinson , Tracey S. Hanks
- Applicant Address: US PA York
- Assignee: DENTSPLY International Inc.
- Current Assignee: DENTSPLY International Inc.
- Current Assignee Address: US PA York
- Agent Leana Levin; Douglas J. Hura; David A. Zdurne
- Main IPC: A61C5/04
- IPC: A61C5/04 ; A61L27/58 ; A61L27/48

Abstract:
A bone repair material is described that is of putty-like consistency, particularly useful for repairing dental bony defects such as those caused by bone loss resulting from moderate or severe periodontitis, augmenting of bony defects of the alveolar ridge, filling tooth extraction sites, or sinus elevation grafting. The repair material includes a porous, resorbable particulate that is bone-derived or derived from bone-like hydroxyapatite or synthetic hydroxyapatite; and, a resorbable carrier, such as high molecular weight polysaccharides, such as hyaluronic acid. A high concentration of particulate in the putty enhances bone repair and requires a high concentration of carrier to retain the putty at the defect site. For a particulate density of about 1.2 g/cc such as PEPGEN P-15® Bone Graft, a preferred formulation comprises about 55% percent by weight of the putty suspended in a hyaluronic acid gel of about 1.4×106 daltons molecular weight and a final concentration of about 56 mg/cc which material adheres to a bony periodontal defect and does not excessively expand or migrate from the defect when held in place by a conventional flap closure.
Public/Granted literature
- US20120101535A1 BONE REPAIR PUTTY Public/Granted day:2012-04-26
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