Invention Grant
- Patent Title: Patch and method for producing the same
- Patent Title (中): 补片及其制作方法
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Application No.: US13923828Application Date: 2013-06-21
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Publication No.: US08877235B2Publication Date: 2014-11-04
- Inventor: Kazunosuke Aida , Terumitsu Kaiho , Tetsurou Tateishi , Nobuo Tsutsumi
- Applicant: Hisamitsu Pharmaceutical Co., Inc.
- Applicant Address: JP Tosu-shi
- Assignee: Hisamitsu Pharmaceutical Co., Inc.
- Current Assignee: Hisamitsu Pharmaceutical Co., Inc.
- Current Assignee Address: JP Tosu-shi
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2012-284766 20121227
- Main IPC: A61K9/70
- IPC: A61K9/70 ; A61F13/02 ; A61K9/00 ; A61K31/216

Abstract:
A method for producing a patch comprising a support layer and an adhesive agent layer arranged on at least one surface of the support layer, the method comprising: a step A of obtaining an adhesive agent layer composition comprising oxybutynin hydrochloride as a drug, an acrylic-based polymer and/or a rubber-based polymer as an adhesive base agent, liquid paraffin, a sterol, an organic acid, and a tackifier; a step B of heating the adhesive agent layer composition at a temperature in a range from 55 to 70° C. for 1 to 24 hours; and a step C of cooling the heated adhesive agent layer composition to a temperature lower than room temperature at an average rate of temperature drop of 1 to 20° C./hour, thereby obtaining the adhesive agent layer comprising the drug at a supersaturated concentration in a dissolved form.
Public/Granted literature
- US20140186428A1 PATCH AND METHOD FOR PRODUCING THE SAME Public/Granted day:2014-07-03
Information query