Invention Grant
US08877466B2 Bacterial cells having a glyoxylate shunt for the manufacture of succinic acid
有权
具有用于制备琥珀酸的乙醛酸分流的细菌细胞
- Patent Title: Bacterial cells having a glyoxylate shunt for the manufacture of succinic acid
- Patent Title (中): 具有用于制备琥珀酸的乙醛酸分流的细菌细胞
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Application No.: US12644059Application Date: 2009-12-22
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Publication No.: US08877466B2Publication Date: 2014-11-04
- Inventor: Edzard Scholten , Stefan Haefner , Hartwig Schröder
- Applicant: Edzard Scholten , Stefan Haefner , Hartwig Schröder
- Applicant Address: DE Ludwigshafen
- Assignee: BASF SE
- Current Assignee: BASF SE
- Current Assignee Address: DE Ludwigshafen
- Agency: Drinker Biddle & Reath LLP
- Priority: EP08172793 20081223
- Main IPC: C12P7/46
- IPC: C12P7/46 ; C12N1/20 ; C12P21/06 ; C12P19/34 ; C12N15/00 ; C07H21/04 ; C12N9/88 ; C12N9/10 ; C12N9/02
Abstract:
The present invention is concerned with bacteria for the production of succinic acid. Specifically, the invention relates to a bacterial cell of the genus Pasteurella comprising a heterologous polypeptide having isocitrate lyase activity and a heterologous polypeptide having malate synthase activity. Further, the present invention contemplates a polynucleotide comprising a nucleic acid encoding a polypeptide having isocitrate lyase activity and a nucleic acid encoding a polypeptide having malate synthase activity. Finally, the present invention relates to the use of a bacterial cell of the invention for the manufacture of succinic acid.
Public/Granted literature
- US20100159543A1 BACTERIAL CELLS HAVING A GLYOXYLATE SHUNT FOR THE MANUFACTURE OF SUCCINIC ACID Public/Granted day:2010-06-24
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