Invention Grant
- Patent Title: Homo-succinic acid producing microorganism variant and process for preparing succinic acid using the same
- Patent Title (中): 产琥珀酸的微生物变异体及使用其制备琥珀酸的方法
-
Application No.: US12668868Application Date: 2008-01-15
-
Publication No.: US08877482B2Publication Date: 2014-11-04
- Inventor: Sang Yup Lee , Ji Mahn Kim , Jeong Wook Lee , Hyohak Song , Sol Choi
- Applicant: Sang Yup Lee , Ji Mahn Kim , Jeong Wook Lee , Hyohak Song , Sol Choi
- Applicant Address: KR Daejeon
- Assignee: Korea Advanced Institute of Science and Technology
- Current Assignee: Korea Advanced Institute of Science and Technology
- Current Assignee Address: KR Daejeon
- Agency: Rabin & Berdo, P.C.
- Priority: KR10-2007-0070219 20070712
- International Application: PCT/KR2008/000241 WO 20080115
- International Announcement: WO2009/008574 WO 20090115
- Main IPC: C12N1/20
- IPC: C12N1/20 ; C12N15/00 ; C12N15/74 ; C12P7/46 ; C12N9/04 ; C12N9/12
Abstract:
The present invention relates to microbial variants producing homo-succinic acid at high yields and a method for producing homo-succinic acid using the same, more particularly, to a microbial variant constructed by disrupting a lactate dehydro-genase-encoding gene (idhA) and an acetate kinase-encoding gene (ackA), as well as a method for producing homo-succinic acid at high concentration, which comprises culturing such variants using glucose as a carbon source in anaerobic conditions.
Public/Granted literature
Information query
IPC分类:
