Invention Grant
US08877504B2 Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to toxic molecule
有权
用于选择重组克隆的方法，其包含编码毒性分子的解毒剂蛋白的序列
- Patent Title: Method for the selection of recombinant clones comprising a sequence encoding an antidote protein to toxic molecule
- Patent Title (中): 用于选择重组克隆的方法，其包含编码毒性分子的解毒剂蛋白的序列
-
Application No.: US13919952Application Date: 2013-06-17
-
Publication No.: US08877504B2Publication Date: 2014-11-04
- Inventor: Philippe Gabant , Laurence Van Melderen , Cedric Yves Szpirer
- Applicant: Universite Libre de Bruxelles
- Applicant Address: BE Brussels
- Assignee: Universite Libre de Bruxelles
- Current Assignee: Universite Libre de Bruxelles
- Current Assignee Address: BE Brussels
- Agency: Knobbe, Martens, Olson & Bear LLP
- Main IPC: C12N15/70
- IPC: C12N15/70 ; C07K14/245 ; C12N15/10 ; C12N15/65 ; C12N15/66 ; C07H21/04
Abstract:
The present invention is related to a method for the selection of recombinant clones having integrated a gene of interest and a nucleotide sequence encoding a functional antidote protein to a toxic molecule, wherein said recombinant clones are the ones which survive following their integration into a host cell comprising in its genome a nucleotide sequence encoding said toxic molecule. The present invention is also related to a nucleic acid construct, a vector comprising said nucleic acid construct, a host cell and a cloning and/or sequencing kit for performing said method.
Public/Granted literature
Information query
IPC分类:
