Invention Grant
US08877723B2 Method for identification of sensitivity of a patient to telomerase inhibition therapy
有权
用于鉴定患者对端粒酶抑制治疗的敏感性的方法
- Patent Title: Method for identification of sensitivity of a patient to telomerase inhibition therapy
- Patent Title (中): 用于鉴定患者对端粒酶抑制治疗的敏感性的方法
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Application No.: US13124376Application Date: 2009-10-13
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Publication No.: US08877723B2Publication Date: 2014-11-04
- Inventor: Calvin B. Harley , Laurence Elias , Jennifer Smith , Mark J. Ratain , Fabio Benedetti
- Applicant: Calvin B. Harley , Laurence Elias , Jennifer Smith , Mark J. Ratain , Fabio Benedetti
- Applicant Address: US CA Menlo Park
- Assignee: Geron Corporation
- Current Assignee: Geron Corporation
- Current Assignee Address: US CA Menlo Park
- Agent Leslie A. Mooi
- International Application: PCT/US2009/060526 WO 20091013
- International Announcement: WO2010/045245 WO 20100422
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C07K14/00

Abstract:
The invention provides methods for determining the susceptibility of cancer patients to developing adverse reactions if treated with a telomerase inhibitor drug by measurement of telomere length in appropriate cells of the patient prior to initiation of the telomerase inhibitor treatment.
Public/Granted literature
- US20110263685A1 Method for Identification of Sensitivity of a Patient to Telomerase Inhibition Therapy Public/Granted day:2011-10-27
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