Invention Grant
- Patent Title: Combination, kit and method of reducing intraocular pressure
- Patent Title (中): 降低眼内压的组合，试剂盒和方法
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Application No.: US13004380Application Date: 2011-01-11
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Publication No.: US08877732B2Publication Date: 2014-11-04
- Inventor: Norman N. Kim , William K. McVicar , Thomas G. McCauley , Rudolf A. Baumgartner
- Applicant: Norman N. Kim , William K. McVicar , Thomas G. McCauley , Rudolf A. Baumgartner
- Applicant Address: US MA Lexington
- Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee Address: US MA Lexington
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Cynthia L. Kanik
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/24 ; A61K31/215 ; A61K31/235 ; A01N43/04 ; A01N37/08 ; A01N37/10 ; A61K9/00 ; A61K45/06 ; A61K31/7076 ; A61K31/19 ; A61K31/165 ; A61K31/216 ; A01N37/12 ; A01N37/44
Abstract:
The present invention is directed to a combination or a kit comprising a prostaglandin analog and an adenosine receptor A1 agonist and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. In one embodiment, the prostaglandin analog is latanoprost and the adenosine receptor A1 agonist is Compound A, ((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate, having the structure,
Public/Granted literature
- US20110172177A1 COMBINATION, KIT AND METHOD OF REDUCING INTRAOCULAR PRESSURE Public/Granted day:2011-07-14
Information query
