Invention Grant
US08877745B2 CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
有权
CCR2受体拮抗剂，其制备方法及其作为药物的用途
- Patent Title: CCR2 receptor antagonists, method for producing the same, and use thereof as medicaments
- Patent Title (中): CCR2受体拮抗剂，其制备方法及其作为药物的用途
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Application No.: US13696859Application Date: 2011-05-10
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Publication No.: US08877745B2Publication Date: 2014-11-04
- Inventor: Heiner Ebel , Sara Frattini , Riccardo Giovannini , Christoph Hoenke , Rocco Mazzaferro , Stefan Scheuerer
- Applicant: Heiner Ebel , Sara Frattini , Riccardo Giovannini , Christoph Hoenke , Rocco Mazzaferro , Stefan Scheuerer
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Edward S. Lazer
- Priority: EP10162629 20100512
- International Application: PCT/EP2011/057545 WO 20110510
- International Announcement: WO2011/141474 WO 20111117
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/506 ; C07D495/04 ; C07D491/10 ; C07D413/14 ; C07D401/14 ; C07D487/04 ; C07D405/14 ; C07D491/107
Abstract:
The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) of formula (I) wherein HET is a group selected from among formulas (IIa) (IIb) (IIc) (IId) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD and pain diseases.
Public/Granted literature
- US20130123241A1 NOVEL CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS Public/Granted day:2013-05-16
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