Invention Grant
- Patent Title: Titration package for neramexane and its use in the treatment of an inner ear disorder
- Patent Title (中): 奈拉美生的滴定包及其用于治疗内耳障碍
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Application No.: US12733645Application Date: 2008-09-10
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Publication No.: US08877814B2Publication Date: 2014-11-04
- Inventor: Barbara Ellers-Lenz , Tanja Rosenberg , Erhard Seiller , Hagen Kruger , Michael Althaus
- Applicant: Barbara Ellers-Lenz , Tanja Rosenberg , Erhard Seiller , Hagen Kruger , Michael Althaus
- Applicant Address: DE Frankfurt am Main
- Assignee: Merz Pharma GmbH & Co. KGaA
- Current Assignee: Merz Pharma GmbH & Co. KGaA
- Current Assignee Address: DE Frankfurt am Main
- Agency: Hueschen and Sage
- Priority: EP07253630 20070912; EP08004776 20080314; EP08004777 20080314; EP08004778 20080314
- International Application: PCT/EP2008/007420 WO 20080910
- International Announcement: WO2009/033651 WO 20090319
- Main IPC: A61K31/13
- IPC: A61K31/13 ; A61P27/16 ; C07C211/35 ; A61K9/20

Abstract:
The present invention relates to a titration scheme for the administration of a 1-amino-alkylcyclohexane derivative which allows for quick attainment of an effective dose of a 1-amino-alkylcyclohexane derivative while minimizing side effects. The present invention further relates to a titration package for providing a 1-amino-alkylcyclohexane derivative (e.g., neramexane or a pharmaceutically acceptable salt thereof) in at least two different dosages. The present titration scheme/titration package may be useful in the treatment of various diseases, including tinnitus.
Public/Granted literature
- US20100298441A1 TITRATION PACKAGE FOR NERAMEXANE AND ITS USE IN THE TREATMENT OF AN INNER EAR DISORDER Public/Granted day:2010-11-25
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