Invention Grant
- Patent Title: Modified beta-lactoglobulins for immunotherapy of milk allergy
- Patent Title (中): 用于牛奶过敏免疫治疗的改良β-乳球蛋白
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Application No.: US12999955Application Date: 2009-06-18
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Publication No.: US08877894B2Publication Date: 2014-11-04
- Inventor: Juha Rouvinen , Kristiina Takkinen , Merja Niemi , Sirpa Jylhä , Hans Söderlund , Marja-Leena Laukkanen
- Applicant: Juha Rouvinen , Kristiina Takkinen , Merja Niemi , Sirpa Jylhä , Hans Söderlund , Marja-Leena Laukkanen
- Applicant Address: FI VTT
- Assignee: Teknologian Tutkimuskeskus VTT
- Current Assignee: Teknologian Tutkimuskeskus VTT
- Current Assignee Address: FI VTT
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FI20085601 20080618
- International Application: PCT/FI2009/050549 WO 20090618
- International Announcement: WO2009/153414 WO 20091223
- Main IPC: C07K14/00
- IPC: C07K14/00 ; G06G7/58 ; A61K39/36 ; C07K14/47 ; A61K39/35
Abstract:
The present invention is related to field of allergic (hypersensitivity) diseases and provides a method for producing modified allergenic polypeptides for use in immunotherapies. In the method of the invention, said allergenic polypeptides are modified so that they are not capable to form transient dimers. The invention also provides modified β-lactoglobulins for use in immunotherapy of milk allergy.
Public/Granted literature
- US20110104190A1 MODIFIED BETA-LACTOGLOBULINS FOR IMMUNOTHERAPY OF MILK ALLERGY Public/Granted day:2011-05-05
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