Invention Grant
- Patent Title: Chromatography purification of antibodies
- Patent Title (中): 抗体的色谱纯化
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Application No.: US13460474Application Date: 2012-04-30
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Publication No.: US08877904B2Publication Date: 2014-11-04
- Inventor: Peter S. Gagnon , Hong Chen , Russ Frost
- Applicant: Peter S. Gagnon , Hong Chen , Russ Frost
- Applicant Address: US CA Hercules
- Assignee: Bio-Rad Laboratories, Inc.
- Current Assignee: Bio-Rad Laboratories, Inc.
- Current Assignee Address: US CA Hercules
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: A23J1/00
- IPC: A23J1/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; C07K1/36 ; B01D15/36 ; B01D15/38 ; C07K16/06 ; A61K39/395 ; C07K1/14

Abstract:
Methods, kits and apparatuses for chromatography purification of antibodies are provided. In some embodiments, antibodies are purified by mixed mode chromatography that does not comprise hydroxyapatite (HT) or fluorapatite (FT). The mixed mode chromatography step is then followed by a HT/FT chromatography step.
Public/Granted literature
- US20120264915A1 CHROMATOGRAPHY PURIFICATION OF ANTIBODIES Public/Granted day:2012-10-18
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