A mechanism is provided in a data processing system for reliable asynchronous solid-state device based de-duplication. Responsive to receiving a write request to write data to the file system, the mechanism sends the write request to the file system, and in parallel, computes a hash key for the write data. The mechanism looks up the hash key in a de-duplication table. The de-duplication table is stored in a memory or a solid-state storage device. Responsive to the hash key not existing in the de-duplication table, the mechanism writes the write data to a storage device, writes a journal transaction comprising the hash key, and updates the de-duplication table to reference the write data in the storage device.