Invention Grant
US08889854B2 C-17 bicyclic amines of triterpenoids with HIV maturation inhibitory activity
有权
具有HIV成熟抑制活性的三萜类化合物的C-17二环胺
- Patent Title: C-17 bicyclic amines of triterpenoids with HIV maturation inhibitory activity
- Patent Title (中): 具有HIV成熟抑制活性的三萜类化合物的C-17二环胺
-
Application No.: US13799479Application Date: 2013-03-13
-
Publication No.: US08889854B2Publication Date: 2014-11-18
- Inventor: Ny Sin , Zheng Liu , Jacob Swidorski , Sing-Yuen Sit , Jie Chen , Yan Chen , Nicholas A. Meanwell , Alicia Regueiro-Ren
- Applicant: Bristol-Myers Squibb Company
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent John F. Levis
- Main IPC: C07J53/00
- IPC: C07J53/00 ; C07D498/08 ; C07D495/08 ; C07D495/10 ; C07D487/10 ; C07J63/00 ; C07D491/08 ; C07D209/52 ; C07D487/08
Abstract:
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-17 bicyclic amines of triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II and III: These compounds are useful for the treatment of HIV and AIDS.
Public/Granted literature
- US20130296554A1 C-17 BICYCLIC AMINES OF TRITERPENOIDS WITH HIV MATURATION INHIBITORY ACTIVITY Public/Granted day:2013-11-07
Information query
