A new approach is proposed that contemplates systems and methods to support video-aware screen capture and compression. More specifically, the video-aware approach first detects whether or when video content is being actively played back on a screen of a hosting device. If the video content is actively being rendered, the approach separates (segments) the screen content into static (non-video) content and video content, The approach then applies video-specific capture and compression methods to the video content of the screen and other suitable compression methods to the non-video content of the screen. The compressed static and video content of the screen are separately and independently transmitted across the network to remote computing devices and are then decompressed and processed to reconstruct screen of its original content for display at the screens of the remote computing devices.