A control panel and a serial port communication arbiter for a touch screen with a camera are provided. A serial port communication method for a touch screen with a camera includes: transmitting a channel request message to the serial port communication arbiter, the channel request message being used for requesting for occupying the channel between the control panel of the touch screen with camera and an upper computer; receiving a channel response message transmitted by the serial port communication arbiter, the channel response message containing a state of the channel; transmitting data to the upper computer over the channel if the state of the channel is idle. It can save production cost of the control panel, improve system performance, and facilitate maintenance of the control panel.