A Multi-Tile Power Management Integrated Circuit (MTPMIC) includes a processor, a fault protect circuit, a first terminal, a driver that drives the first terminal, a second terminal, and detection circuitry that outputs a digital detection signal indicative of whether a predetermined condition is detected on the second terminal. The processor can program the fault protect circuit so that the fault protect circuit will later disable the driver as a function of multiple signals, including the digital detection signal. The function is programmable by the processor. In one example, if the detection circuitry detects the predetermined condition on the second terminal then the fault protect circuit disables all the high-side drivers and all low-side drivers of the MTPMIC independently of and without input from the processor.