Methods and systems are described herein for detecting one or more analyte in salivary fluid. Systems include: a discrete oral component configured for complete enclosure in a human oral cavity; at least one sensor configured to detect one or more analyte in salivary fluid; and an external device including a port configured for communication with the discrete oral component. Methods include: detecting one or more analyte within salivary fluid with at least one sensor integral to a discrete oral component, wherein the discrete oral component is configured to be completely enclosed in the oral cavity and includes one or more flavorant; and communicating information from the discrete oral component to at least one external device.