Invention Grant
- Patent Title: Indole derivatives as inhibitors of histone deacetylase
- Patent Title (中): 吲哚衍生物作为组蛋白脱乙酰酶的抑制剂
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Application No.: US13683880Application Date: 2012-11-21
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Publication No.: US08900565B2Publication Date: 2014-12-02
- Inventor: Joseph J. Buggy , Sriram Balasubramanian , Erik Verner , Vincent W. F. Tai , Chang-Sun Lee
- Applicant: Pharmacyclics, Inc.
- Applicant Address: US CA Sunnyvale
- Assignee: Pharmacyclics, Inc.
- Current Assignee: Pharmacyclics, Inc.
- Current Assignee Address: US CA Sunnyvale
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: A61K31/405
- IPC: A61K31/405 ; A61K31/55 ; A61K45/06 ; C07D209/08 ; C07D209/42 ; A61K31/5377 ; C07D209/12 ; A61K31/404 ; C07D209/14
Abstract:
Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of histone deacetylase 8 (HDAC8). Also described herein are methods of using such HDAC8 inhibitors, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of HDAC8 activity.
Public/Granted literature
- US20130156727A1 INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE Public/Granted day:2013-06-20
Information query
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